PlantForm in the News
November 17, 2023:
Leveraging Plant-Based Protein Expression: Implications for Biomanufacturing and Biodefense
March 23, 2023:
UFC and FIOCRUZ/Bio-Manguinhos sign cooperation agreement; goal is to develop drugs for cancer treatment
March 8, 2023:
Guelph company helping make cancer drug cheaper in Brazil
June 6, 2022:
Pigs fed E. coli antibodies could lead to safer pork
Canadian Hog Journal
May 10, 2022:
Growing outside the box
Greenhouse Canada
January 17, 2022:
Antibody discovery aims to treat E. coli in pigs for improved livestock health and human safety
Government of Canada | Agriculture and Agri-Food Canada News
February 4, 2021:
Feed additive in development to reduce food safety risks
Farmtario
December 26, 2020:
Research project targets E. coli infection in pigs
Pig Progress
December 19, 2020:
PlantForm, AAFC research project targets E. coli infection in pigs
Food in Canada
December 17, 2020:
Feed additive research will target E. coli infection in pigs
realagriculture.com
December 2, 2020:
NSERC Awards Alliance Grant to PlantForm to Enable Commercial-Scale Production of Protein Therapeutics
PharmaTech.com
June 18, 2020:
Promising treatments for COVID-19 advanced by Canadian scientists
The Globe and Mail
May 13, 2020:
Amazing ways Canadian startups are tackling the COVID-19 crisis
MaRS Magazine
April 28, 2020:
Biotech company with ties to Sarnia joins COVID-19 fight
BlackburnNews.com
April 20, 2020:
South Africa: Entrepreneurs Pioneer Rapid COVID-19 Test Kit
AllAfrica.com
April 14, 2020:
Tools to end the lockdown
CBC The Current with Matt Galloway
April 14, 2020:
A company that produces antibodies is joining the fight against COVID-19
KitchenerToday.com
April 11, 2020:
Guelph biotech firm working to develop coronavirus blood test
Guelph Mercury-Tribune
April 7, 2020:
Guelph, Ont., company to develop blood test for COVID-19 immunity
Global News.ca
January 28, 2020:
There's A Lot to Like About International Year of Plant Health
The Grower
May 9, 2018:
PlantForm receives European patent for tobacco plant-based platform
Biopharma-Reporter.com
May 8, 2018:
Plantform Corporation receives patent from the European Patent Office
Laboratory Focus
January 5, 2018:
Plant-made pharma specialist faces challenges of outsourcing to grow business
Laboratory Focus
January 3, 2018:
2018 Outlook: Biosimilar Trends To Watch
Biosimilar Development
December 28, 2017:
Did The 2017 Biosimilar Industry Pave The Way For A Productive 2018?
Biosimilar Development
August 9, 2017:
Plant-Based Biosimilar Development Takes Root In Brazil
Biosimilar Development
June 21, 2017:
Brazilian plant to make Humira biosimilar in 'tobacco-based bioreactors'
Biopharma-Reporter.com
June 20, 2017:
Major step in the evolution of plant-based pharmaceuticals
GuelphToday.com
June 19, 2017:
Construction of PlantForm-Axis Biotech’s Brazilian biosimilar lab begins
Biotechnology Focus
August 9, 2016:
Biotech firm leverages Ontario talent for global success
Invest in Ontario
August 3, 2016:
#HumansofMaRS: Plantform is building Canadian-based biotech for international markets
MaRS Blog
July 12, 2016:
Special Report on Cell Biology: Sweetening the pot
DDNews
May 9, 2016:
Navigating Brazil's Emerging Biosimilar Market
Biosimilar Development
May 2, 2016:
"Growing" Biosimilars: How Plants Bolster Manufacturing Efficiency
Biosimilar Development
March 1, 2016:
Grown in Guelph: Tobacco plants that fight terrorist tactics and cancer
Guelph Today
June 15, 2015:
Guelph firm PlantForm making great strides in fight against Ebola Sudan
Guelph Mercury
May 4, 2015:
These Bioengineered Tobacco Plants are Growing Pharmaceuticals of the Future
Motherboard
April 9, 2015:
Feds back PlantForm's development of antibody treatments for HIV strains
Biotechnology Focus.ca
April 5, 2015:
Guelph biotech firm’s HIV work gets funding
Guelph Mercury
March 17, 2015:
Tobacco plants to fight Ebola, nerve gas exposure
Ag Innovation Ontario
February 20, 2015:
Guelph company developing life-saving drugs from tobacco plants
Ag Innovation Ontario
December 11, 2014:
Guelph firm growing nerve-gas protection
Guelph Mercury
November 17, 2014:
Researchers Turn to Deadly Tobacco for Ebola Cure
Voice of America | Zimbabwe
October 18, 2014:
How tobacco plants can help fight Ebola
CTV National News
October 3, 2014:
Tobacco plant may be key to Ebola drugs
CNN.com
August 22, 2014:
Plant-made drugs could be the future
Al Jazeera America
August 22, 2014:
More biosimilars collaborations on the cards
GaBI online
August 17, 2014:
'Plantibodies' drugs advance as big pharma stands aside
Reuters
July 23, 2014:
Brazilian JV looks to tap plant-based manufacturing system for biosimilars
BioPharma-Reporter.com
July 8, 2014:
An interview with Don Stewart, President, CEO, and founder of PlantForm Corporation
The Biosimilarz Blog!
July 2, 2014:
PlantForm and PharmaPraxis Establish Joint Biosimilar Development Venture
BioPharm International.com
June 11, 2014:
A round-up of innovative medical developments happening right here in Toronto
YongeStreet
May 19, 2014:
Biosimilars: 11 drugs to watch
Genetic Engineering & Biotechnology News
May 13, 2014:
Biotech Angels at work-on uppers or downers? And can you change their meds?
Biotechnology Focus
December 3, 2013:
Game Changers in Agriculture Profiles PlantForm Corporation
Ontario Agri-Food Technologies/BioTalk.ca video
August 21, 2013:
PlantForm attracts investment for cancer drug
Guelph Mercury
August 13, 2013:
PlantForm gets more funding for HIV antibodies
Guelph Mercury
May 24, 2013:
PlantForm PharmaPraxis agree to improve drugs as a team
Biotechnology Focus
May 17, 2013:
Pharming New Fields
BioBusiness Magazine
May 15, 2013:
PlantForm: Curing cancer with tobacco
OntarioInnovation
May 12, 2013:
Tobacco can cure cancer
Contact, Accessible Media Inc. (audio)
January 31, 2013:
Healing Power of Plants
The agAdvance
January 21, 2013:
Interview with CEO Don Stewart
CEOCFO Magazine
January 19, 2013:
Tobacco cancer drug
Global Toronto News Hour
January 11, 2013:
Ontario scientists using tobacco to replicate common breast cancer drug
Global News
January 8, 2013:
Tobacco goes pink
Research magazine, 2012-13 Agri-Food Yearbook Edition
November 27, 2012:
PlantForm to develop medical countermeasure against chemical threats
Biotechnology Focus
November 19, 2012:
U.S. defence agency looks to Guelph to develop nerve gas antidote
Guelph Mercury
October 10, 2012:
Biologics and biologic products
OSMT Advocate
May 18, 2012:
Venture Forum aids first impressions
The Buffalo News
February 29, 2012:
Your Money Matters: PlantForm profile
570 News (radio interview with CEO Don Stewart)
February 23, 2012:
Guelph firm seeks to use tobacco to fight cancer
Guelph Mercury
January 31, 2012:
Can tobacco be used to cure cancer?
The Globe and Mail
December 15, 2011:
Plant-made pharmaceuticals: an ongoing debate
Ag-West Bio Bio-Bulletin
October 16, 2011:
PlantForm gearing up to ‘grow’ breast cancer drug using tobacco as a host
Lambton Shield.com
September 21, 2011:
The kinder side of tobacco
An independent supplement by MediaPlanet to the National Post
May 15, 2011:
Biosimilars Proceed With Caution From Starting Gate
Genetic Engineering & Biotechnology News
March 21, 2011:
Business innovation through R&D tax credits
CBC Radio, World at Six report
January 4, 2011:
Fighting cancer with tobacco
Ontario Ministry of Economic Development & Trade
June 24, 2010:
Business gala shines spotlight on the city's bright lights
Guelph Mercury
May 1, 2009:
Platform for growth
Rex Magazine
Publications
Bacterial growth-mediated systems remodelling of Nicotiana benthamiana defines unique signatures of target protein production in molecular pharming. Nicholas Prudhomme, Rebecca Pastora, Sarah Thomson, Edison Zheng, Amanda Sproule, Jonathan R. Krieger, J. Patrick Murphy, David P. Overy, Doug Cossar, Michael D. McLean, Jennifer Geddes-McAlister. Plant Biotechnology Journal 22 March 2024
The emerging role of mass spectrometry-based proteomics in molecular pharming practices. Jennifer Geddes-McAlister, NicholasPrudhomme, Davier Gutierrez Gongora, DougCossar, Michael D.McLean. Current Opinion in Chemical Biology Volume 68, June 2022
Enhanced ability of plant-derived PGT121 glycovariants to eliminate HIV-1-infected cells. Sai Priya Anand, Shilei Ding, William D. Tolbert, Jérémie Prévost, Jonathan Richard, Hwi Min Gil, Gabrielle Gendron-Lepage, Wing-Fai Cheung, Haifeng Wang, Rebecca Pastora, Hirak Saxena, Warren Wakarchuk, Halima Medjahed, Bruce D. Wines, P. Mark Hogarth, George M. Shaw, Malcom A. Martin, Dennis R. Burton, Lars Hangartner, David T. Evans, Marzena Pazgier, Doug Cossar, Michael D. McLean, Andrés Finzi. Journal of Virology July 7, 2021
Quantitative proteomic profiling of shake-flask versus bioreactor growth reveals distinct responses of Agrobacterium tumefaciens for preparation in molecular pharming. Nicholas Prudhomme, Connor Gianetto-Hill, Rebecca Pastora, Wing-Fai Cheung, Emma Allen-Vercoe, Michael D McLean, Doug Cossar, Jennifer Geddes-McAlister. Canadian Journal of Microbiology 2020 Aug 26. doi: 10.1139/cjm-2020-0238. Online ahead of print.
Exposure of Agrobacterium tumefaciens to agroinfiltration medium demonstrates cellular remodeling and may promote enhanced adaptability for molecular pharming. Nicholas Prudhomme, Rebecca Pastora, Benjamin Muselius, Mike McLean, Doug Cossar, Jennifer Geddes-McAlister. Canadian Journal of Microbiology 2020 Jul 28. doi: 10.1139/cjm-2020-0239. Online ahead of print.
A Broad and Potent H1-Specific Human Monoclonal Antibody Produced in Plants Prevents Influenza Virus Infection and Transmission in Guinea Pigs. Jun-Gyu Park, Chengjin Ye, Michael S. Piepenbrink, Aitor Nogales, Haifeng Wang, Michael Shuen, Ashley J. Meyers, Luis Martinez-Sobrido, James J. Kobie. Viruses 020 Feb; 12(2): 167
Trastuzumab Made in Plants Using vivoXPRESS® Platform Technology. McLean MD. J Drug Des Res 4(5): 1052 (2017)
Plant-based Production of Biosimilar Drug Products. So Kenny KY, Marit MR, McLean MD, Hall JC. Chapter 17 in Biosimilar Drug Product Development, Eds. Endrenyi L, Declerck PJ, Chow SC.
The case for plant-made veterinary immunotherapeutics. Topp E, Irwin R, McAllister T, Lessard M, Joensuu JJ, Kolotilin I, Conrad U, Stöger E, Mor T, Warzecha H, Hall JC, McLean MD, Cox E, Devriendt B, Potter A, Depicker A, Virdi V, Holbrook L, Doshi K, Dussault M, Friendship R, Yarosh O, Yoo HS, MacDonald J, Menassa R. Biotechnology Advances, Sept.-Oct. 2016. 34 (5): 597-604.
Waiving in vivo studies for monoclonal antibody biosimilar development: National and global challenges. Kathryn Chapman, Akosua Adjei, Paul Baldrick, Antonio da Silva, Karen De Smet, Richard DiCicco, Seung Suh Hong, David Jones, Michael W. Leach, James McBlane, Ian Ragan, Praveen Reddy, Donald I. H. Stewart, Amanda Suitters, Jennifer Sims. mAbs journal, 06 February 2016
Bringing plant-based veterinary vaccines to market: Managing regulatory and commercial hurdles. Jacqueline MacDonald, Ketan Doshi, Marike Dussault, J. Christopher Hall, Larry Holbrook, Ginny Jones, Angelo Kaldis, Cassidy L. Klima, Phil Macdonald, Tim McAllister, Michael D. McLean, Andrew Potter, Alex Richman, Heather Shearer, Oksana Yarosh, Han Sang Yoo, Edward Topp, Rima Menassa. Biotechnology Advances, December 2015. 33 (8): 1572-81.
Plant-based solutions for veterinary immunotherapeutics and prophylactics. Igor Kolotilin, Ed Topp, Eric Cox, Bert Devreindt, Udo Conrad, Jussi Joensuu, Eva Stöger, Heribert Warzecha, Tim McAllister, Andrew Potter, Michael D McLean, J Christopher Hall, Rima Menassa. Veterinary Research 2014, 45:117, Dec. 31, 2014
In Vivo Neutralization of a-Cobratoxin with High-Affinity Llama Single-Domain Antibodies (VHHs) and a VHH-Fc Antibody. Richard G, Meyers AJ, McLean MD, Arbabi-Ghahroudi M, MacKenzie R, Hall JC. PLOS ONE, July 2013
Utility of the P19 suppressor of gene-silencing protein for production of therapeutic antibodies in Nicotiana expression hosts. Freydoun Garabagi, Erin Gilbert, Andreas Loos, Michael D. McLean and J. Christopher Hall. Plant Biotechnology Journal. Sept. 17, 2012
Purification of the therapeutic antibody trastuzumab from genetically modified plants using safflower Protein A-oleosin oilbody technology. Michael D. McLean, Rongji Chen, Deqiang Yu, Kor-Zheng Mah, John Teat, Haifeng Wang, Steve Zaplachinski, Joseph Boothe and J. Christopher Hall Transgenic Research, March 2, 2012
Recovery and isolation of recombinant human monoclonal antibody from transgenic tobacco plants. Mayani M, McLean MD, Hall, JC, Filipe, CDM, Ghosh, R. Biochemical Engineering Journal, April 15, 2011
Plant-Produced Trastuzumab Inhibits the Growth of HER2 Positive Cancer Cells. Grohs BM, Niu Y, Veldhuis LJ, Trabelsi S, Garabagi F, Hassell JA, McLean MD and Hall JC. Journal of Agricultural and Food Chemistry, Aug. 27, 2010
Purification of Plant-Derived Antibodies through Direct Immobilization of Affinity Ligands on Cellulose. Hussack G, Grohs BM, Almquist KC, McLean MD, Ghosh R, Hall JC. Journal of Agricultural and Food Chemistry, Feb. 19, 2010
Complexes with anti-epitope tag IgGs improve the therapeutic potential of epitope-tagged antibody fragments. Xie X, Weisser NE, McLean MD, Hall JC. Molecular Immunology, January 2010